At a brief ceremony in the Darbar Hall of Rashtrapati Bhawan, President Ramnath Kovind administered the oath of office to Misra.
Justice Misra, 64, assumes office following the retirement of Justice J S Khehar yesterday.
Justice Misra will remain in office till October 2, 2018.
As per the established practice, Justice Khehar had named Misra as the next CJI last month. PTI